| Fighter | Record | Last Bout |
|---|---|---|
| Eric Shelton | 12-6-0 | 2019-03-23 |
| Eric Spicely | 12-6-0 | 2019-06-22 |
| Eric Wisely | 26-9-1 | 2012-04-14 |
| Erick Gonzalez | 14-8-0 | 2023-02-25 |
| Erick Montano | 7-5-0 | 2016-11-05 |
| Erick Silva | 19-9-0 (1 NC) | 2017-12-16 |
| Ericka Almeida | 7-3-0 | 2015-10-24 |
| Erik Koch | 16-6-0 | 2019-07-27 |
| Erik Perez | 17-6-0 | 2016-11-05 |
| Ernest Chavez | 10-2-0 | 2014-10-04 |
| Ernie Verdicia | 0-1-0 | 1995-04-07 |
| Estevan Payan | 16-12-0 (1 NC) | 2014-04-19 |
| Eugene Jackson | 15-9-1 | 2002-07-13 |
| Eugenio Tadeu | 2-3-0 (1 NC) | 1998-03-13 |
| Evan Dunham | 18-9-1 | 2020-06-06 |
| Evan Tanner | 32-8-0 | 2008-06-21 |
| Frankie Edgar | 23-11-1 | 2022-11-12 |
| Fred Ettish | 1-1-0 | 1994-03-11 |
| Ian Entwistle | 9-3-0 | 2016-04-10 |
| Jake Ellenberger | 31-15-0 | 2018-08-25 |
| Jarno Errens | 14-6-1 | 2024-08-10 |
| Jessica Eye | 15-11-0 (1 NC) | 2022-07-02 |
| Jodie Esquibel | 6-6-0 | 2019-08-17 |
| Joe Ellenberger | 15-2-0 | 2014-12-13 |
| Johnny Eduardo | 28-13-0 | 2021-10-02 |
| Jon Olav Einemo | 6-3-0 | 2012-01-28 |
| Jordan Espinosa | 15-9-0 (1 NC) | 2021-03-06 |
| Juan Espino | 11-2-0 | 2021-04-17 |
| Justin Edwards | 9-5-0 | 2015-06-06 |
| Justin Eilers | 19-7-1 | 2006-02-04 |
| Konstantin Erokhin | 9-3-0 | 2015-12-11 |
| Lisa Ellis | 15-11-0 | 2015-05-09 |
| Mark Eddiva | 6-3-0 | 2016-03-19 |
| Marvin Eastman | 18-15-1 | 2008-06-21 |
| Mike Easton | 13-6-0 | 2014-06-14 |
| Oliver Enkamp | 7-2-0 | 2018-03-17 |
| Per Eklund | 14-5-1 | 2009-02-21 |
| Ramazan Emeev | 20-6-0 | 2022-06-11 |
| Rashad Evans | 19-8-1 | 2018-06-09 |
| Rob Emerson | 18-12-0 (1 NC) | 2010-03-31 |
| Sijara Eubanks | 8-7-0 | 2021-12-18 |
| Stephanie Egger | 8-5-0 | 2023-12-09 |
| Te Edwards | 6-3-0 | 2019-01-19 |
| Terry Etim | 16-5-0 | 2013-02-16 |
| Tiago dos Santos e Silva | 20-7-2 (1 NC) | 2016-12-09 |
| Tom Egan | 7-5-0 | 2009-01-17 |
| Tonya Evinger | 19-8-0 (1 NC) | 2019-06-01 |
| Yves Edwards | 42-22-1 (1 NC) | 2014-11-22 |