| Fighter | Record | Last Bout |
|---|---|---|
| Abdul-Kerim Edilov | 17-4-0 | 2017-09-02 |
| Andre Ewell | 17-9-0 | 2021-12-18 |
| Andy Enz | 10-4-0 | 2015-01-31 |
| Anna Elmose | 3-2-0 | 2016-11-19 |
| Ashlee Evans-Smith | 6-6-0 | 2023-07-15 |
| Ben Earwood | 12-3-0 | 2000-11-17 |
| Brian Ebersole | 51-18-1 (1 NC) | 2015-06-06 |
| Cameron Else | 10-6-0 | 2022-04-23 |
| Carlos Eduardo Rocha | 9-4-0 | 2012-06-08 |
| Cody East | 12-3-0 | 2016-10-01 |
| Cole Escovedo | 17-9-0 | 2011-11-12 |
| Dan Evensen | 11-4-0 | 2008-12-27 |
| Doug Evans | 13-10-0 | 2007-12-29 |
| Ebenezer Fontes Braga | 13-7-2 | 1998-10-16 |
| Ed Herman | 27-16-0 (1 NC) | 2023-04-15 |
| Eddie Alvarez | 29-6-0 (1 NC) | 2018-07-28 |
| Eddie Gordon | 8-4-0 | 2015-06-27 |
| Eddie Mendez | 8-3-1 (1 NC) | 2013-06-08 |
| Eddie Ruiz | 1-1-0 | 2003-06-06 |
| Eddie Sanchez | 15-8-0 | 2008-12-10 |
| Eddie Wineland | 24-16-1 | 2022-06-18 |
| Eddie Yagin | 16-7-1 | 2012-04-21 |
| Edgar Garcia | 14-5-0 | 2016-01-02 |
| Edilberto de Oliveira | 29-15-2 | 2007-09-19 |
| Edimilson Souza | 15-5-0 | 2015-11-07 |
| Ednaldo Oliveira | 17-3-1 (1 NC) | 2013-08-03 |
| Eduardo Garagorri | 13-2-0 | 2020-11-07 |
| Edward Faaloloto | 2-5-0 | 2011-11-05 |
| Edwin DeWees | 38-17-0 (1 NC) | 2006-11-11 |
| Edwin Figueroa | 9-5-0 | 2013-11-16 |
| Efrain Escudero | 28-12-0 | 2016-04-23 |
| Eiji Mitsuoka | 18-9-2 | 2012-08-11 |
| Eldo Xavier Dias | 0-1-0 | 1994-12-16 |
| Elias Garcia | 6-2-0 | 2018-12-01 |
| Elias Silverio | 13-3-0 | 2015-08-23 |
| Elias Theodorou | 16-3-0 | 2019-05-04 |
| Eliot Marshall | 10-4-0 | 2011-10-29 |
| Elizabeth Phillips | 6-6-0 | 2016-08-20 |
| Elvis Mutapcic | 15-6-1 | 2016-12-03 |
| Elvis Sinosic | 7-11-2 | 2007-04-21 |
| Emil Meek | 9-5-1 (1 NC) | 2020-02-22 |
| Emily Ducote | 13-9-0 | 2024-05-18 |
| Emily Kagan | 3-3-0 | 2015-12-10 |
| Emily Whitmire | 4-5-0 | 2021-09-18 |
| Emmanuel Yarborough | 1-2-0 | 1994-09-09 |
| Enrique Barzola | 17-5-2 | 2020-03-14 |
| Enrique Marin | 10-4-0 | 2016-07-09 |
| Enson Inoue | 12-8-0 | 1997-05-30 |
| Eric Martin | 0-1-0 | 1997-02-07 |
| Eric Schafer | 14-8-2 | 2012-01-20 |