| Fighter | Record | Last Bout |
|---|---|---|
| Johnny Eduardo | 28-13-0 | 2021-10-02 |
| Jon Olav Einemo | 6-3-0 | 2012-01-28 |
| Jordan Espinosa | 15-9-0 (1 NC) | 2021-03-06 |
| Joselyne Edwards | 18-6-0 | 2026-04-25 |
| Josh Emmett | 19-7-0 | 2026-03-14 |
| Juan Espino | 11-2-0 | 2021-04-17 |
| Julian Erosa | 31-14-0 | 2026-03-28 |
| Justin Edwards | 9-5-0 | 2015-06-06 |
| Justin Eilers | 19-7-1 | 2006-02-04 |
| Konstantin Erokhin | 9-3-0 | 2015-12-11 |
| Leon Edwards | 22-6-0 (1 NC) | 2025-11-15 |
| Lisa Ellis | 15-11-0 | 2015-05-09 |
| Mark Eddiva | 6-3-0 | 2016-03-19 |
| Marvin Eastman | 18-15-1 | 2008-06-21 |
| Mike Easton | 13-6-0 | 2014-06-14 |
| Movsar Evloev | 20-0-0 | 2026-10-24 |
| Oban Elliott | 12-5-0 | 2026-08-01 |
| Oliver Enkamp | 7-2-0 | 2018-03-17 |
| Per Eklund | 14-5-1 | 2009-02-21 |
| Rafael Estevam | 14-1-0 | 2026-04-04 |
| Ramazan Emeev | 20-6-0 | 2022-06-11 |
| Rashad Evans | 19-8-1 | 2018-06-09 |
| Rob Emerson | 18-12-0 (1 NC) | 2010-03-31 |
| Sijara Eubanks | 8-7-0 | 2021-12-18 |
| Stephanie Egger | 8-5-0 | 2023-12-09 |
| Steve Erceg | 14-5-0 | 2026-07-25 |
| Te Edwards | 6-3-0 | 2019-01-19 |
| Terry Etim | 16-5-0 | 2013-02-16 |
| Tiago dos Santos e Silva | 20-7-2 (1 NC) | 2016-12-09 |
| Tim Elliott | 22-14-1 | 2026-09-12 |
| Tom Egan | 7-5-0 | 2009-01-17 |
| Tonya Evinger | 19-8-0 (1 NC) | 2019-06-01 |
| Yves Edwards | 42-22-1 (1 NC) | 2014-11-22 |