| Fighter | Record | Last Bout |
|---|---|---|
| Eduardo Garagorri | 13-2-0 | 2020-11-07 |
| Edward Faaloloto | 2-5-0 | 2011-11-05 |
| Edwin DeWees | 38-17-0 (1 NC) | 2006-11-11 |
| Edwin Figueroa | 9-5-0 | 2013-11-16 |
| Efrain Escudero | 28-12-0 | 2016-04-23 |
| Eiji Mitsuoka | 18-9-2 | 2012-08-11 |
| Eldo Xavier Dias | 0-1-0 | 1994-12-16 |
| Elias Garcia | 6-2-0 | 2018-12-01 |
| Elias Silverio | 13-3-0 | 2015-08-23 |
| Elias Theodorou | 16-3-0 | 2019-05-04 |
| Eliot Marshall | 10-4-0 | 2011-10-29 |
| Elizabeth Phillips | 6-6-0 | 2016-08-20 |
| Elvis Mutapcic | 15-6-1 | 2016-12-03 |
| Elvis Sinosic | 7-11-2 | 2007-04-21 |
| Emil Meek | 9-5-1 (1 NC) | 2020-02-22 |
| Emily Ducote | 13-9-0 | 2024-05-18 |
| Emily Kagan | 3-3-0 | 2015-12-10 |
| Emily Whitmire | 4-5-0 | 2021-09-18 |
| Emmanuel Yarborough | 1-2-0 | 1994-09-09 |
| Enrique Barzola | 17-5-2 | 2020-03-14 |
| Enrique Marin | 10-4-0 | 2016-07-09 |
| Enson Inoue | 12-8-0 | 1997-05-30 |
| Eric Martin | 0-1-0 | 1997-02-07 |
| Eric Schafer | 14-8-2 | 2012-01-20 |
| Eric Shelton | 12-6-0 | 2019-03-23 |
| Eric Spicely | 12-6-0 | 2019-06-22 |
| Eric Wisely | 26-9-1 | 2012-04-14 |
| Erick Gonzalez | 14-8-0 | 2023-02-25 |
| Erick Montano | 7-5-0 | 2016-11-05 |
| Erick Silva | 19-9-0 (1 NC) | 2017-12-16 |
| Ericka Almeida | 7-3-0 | 2015-10-24 |
| Erik Koch | 16-6-0 | 2019-07-27 |
| Erik Perez | 17-6-0 | 2016-11-05 |
| Ernest Chavez | 10-2-0 | 2014-10-04 |
| Ernie Verdicia | 0-1-0 | 1995-04-07 |
| Estevan Payan | 16-12-0 (1 NC) | 2014-04-19 |
| Eugene Jackson | 15-9-1 | 2002-07-13 |
| Eugenio Tadeu | 2-3-0 (1 NC) | 1998-03-13 |
| Evan Dunham | 18-9-1 | 2020-06-06 |
| Evan Tanner | 32-8-0 | 2008-06-21 |
| Fabiano Iha | 9-5-0 | 2001-09-28 |
| Fabiano Scherner | 11-10-0 (3 NC) | 2006-05-27 |
| Fabio Cherant | 7-4-0 | 2022-02-12 |
| Fabio Gurgel | 3-2-0 | 1996-09-20 |
| Fabio Maldonado | 23-11-0 | 2015-11-07 |
| Fabricio Camoes | 14-9-1 | 2014-10-25 |
| Fabricio Werdum | 24-9-1 | 2020-07-25 |
| Falaniko Vitale | 30-11-0 | 2003-11-21 |
| Felice Herrig | 14-10-0 | 2022-06-04 |
| Felicia Spencer | 9-3-0 | 2021-11-13 |