| Fighter | Record | Last Bout |
|---|---|---|
| Duane Ludwig | 21-14-0 | 2012-09-29 |
| Duda Santana | 3-1-0 | 2019-06-01 |
| Dusko Todorovic | 13-7-0 | 2026-08-01 |
| Dustin Hazelett | 12-7-0 | 2010-12-11 |
| Dustin Jacoby | 22-10-1 | 2026-07-25 |
| Dustin Kimura | 11-3-0 | 2014-12-13 |
| Dustin Neace | 25-21-1 (1 NC) | 2011-12-03 |
| Dustin Ortiz | 19-8-0 | 2019-01-19 |
| Dustin Pague | 12-11-0 | 2013-10-19 |
| Dustin Poirier | 30-10-0 (1 NC) | 2025-07-19 |
| Dustin Stoltzfus | 17-8-0 | 2026-08-15 |
| Dwayne Cason | 1-1-0 | 1997-10-17 |
| Dwight Grant | 11-6-0 | 2022-07-16 |
| Dylan Andrews | 18-7-0 (1 NC) | 2015-05-09 |
| Dylan Budka | 7-5-0 | 2025-02-15 |
| Ebenezer Fontes Braga | 13-7-2 | 1998-10-16 |
| Ed Herman | 27-16-0 (1 NC) | 2023-04-15 |
| Eddie Alvarez | 29-6-0 (1 NC) | 2018-07-28 |
| Eddie Gordon | 8-4-0 | 2015-06-27 |
| Eddie Mendez | 8-3-1 (1 NC) | 2013-06-08 |
| Eddie Ruiz | 1-1-0 | 2003-06-06 |
| Eddie Sanchez | 15-8-0 | 2008-12-10 |
| Eddie Wineland | 24-16-1 | 2022-06-18 |
| Eddie Yagin | 16-7-1 | 2012-04-21 |
| Edgar Chairez | 14-6-0 (1 NC) | 2026-09-12 |
| Edgar Garcia | 14-5-0 | 2016-01-02 |
| Edilberto de Oliveira | 29-15-2 | 2007-09-19 |
| Edimilson Souza | 15-5-0 | 2015-11-07 |
| Edmen Shahbazyan | 16-6-0 | 2026-09-19 |
| Ednaldo Oliveira | 17-3-1 (1 NC) | 2013-08-03 |
| Edson Barboza | 24-15-0 | 2026-08-15 |
| Eduarda Moura | 12-2-0 | 2026-09-19 |
| Eduardo Chapolin | 15-3-0 | 2026-08-15 |
| Eduardo Garagorri | 13-2-0 | 2020-11-07 |
| Edward Faaloloto | 2-5-0 | 2011-11-05 |
| Edwin DeWees | 38-17-0 (1 NC) | 2006-11-11 |
| Edwin Figueroa | 9-5-0 | 2013-11-16 |
| Efrain Escudero | 28-12-0 | 2016-04-23 |
| Eiji Mitsuoka | 18-9-2 | 2012-08-11 |
| Eldo Xavier Dias | 0-1-0 | 1994-12-16 |
| Elias Garcia | 6-2-0 | 2018-12-01 |
| Elias Silverio | 13-3-0 | 2015-08-23 |
| Elias Theodorou | 16-3-0 | 2019-05-04 |
| Elijah Smith | 10-1-0 | 2026-03-14 |
| Eliot Marshall | 10-4-0 | 2011-10-29 |
| Elise Reed | 8-6-0 | 2026-08-22 |
| Elisha Ellison | 5-3-0 | 2026-07-11 |
| Elizabeth Phillips | 6-6-0 | 2016-08-20 |
| Elizeu Zaleski dos Santos | 25-10-1 | 2025-08-02 |
| Elves Brener | 16-6-0 | 2026-09-26 |